Solute carrier family 22 member 16 (SLC22A16)
Homo sapiens — UniProt Q86VW1
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 22 member 16 (SLC22A16) is a protein from Homo sapiens identified by UniProt accession Q86VW1, 577 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q86VW1; gene symbol SLC22A16.
- Organism: Homo sapiens.
- Length: 577 amino acids.
- Top disease associations (Open Targets): reticulocyte count, blood metabolite measurement and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 22 member 16 |
|---|---|
| UniProt accession | Q86VW1 |
| Gene | SLC22A16 |
| Organism | Homo sapiens |
| Length | 577 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.52
- blood metabolite measurement · score 0.51
- Red cell distribution width · score 0.48
- serum metabolite measurement · score 0.45
- reticulocyte measurement · score 0.45
- mean corpuscular volume · score 0.43
- Immature Reticulocyte Fraction Measurement · score 0.40
- mean corpuscular hemoglobin concentration · score 0.39
- mean reticulocyte volume · score 0.38
- HbA1c measurement · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86VW1-F1 | alphafold | PREDICTED | 84.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86VW1.
Amino-acid sequence (577 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC22A16?
The strongest Open Targets associations for SLC22A16 are reticulocyte count, blood metabolite measurement, Red cell distribution width, serum metabolite measurement and reticulocyte measurement.
How long is the SLC22A16 protein?
The Homo sapiens SLC22A16 protein (UniProt Q86VW1) is 577 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86VW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86VW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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