Transmembrane protein 200A (TMEM200A)
Homo sapiens — UniProt Q86VY9
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 200A (TMEM200A) is a protein from Homo sapiens identified by UniProt accession Q86VY9, 491 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q86VY9; gene symbol TMEM200A.
- Organism: Homo sapiens.
- Length: 491 amino acids.
- Top disease associations (Open Targets): coronary atherosclerosis, PHF-tau measurement and sleep duration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 200A |
|---|---|
| UniProt accession | Q86VY9 |
| Gene | TMEM200A |
| Organism | Homo sapiens |
| Length | 491 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- coronary atherosclerosis · score 0.23
- PHF-tau measurement · score 0.17
- sleep duration · score 0.14
- unipolar depression · score 0.14
- gonorrhea · score 0.09
- reaction time measurement · score 0.09
- schizophrenia · score 0.09
- lean body mass · score 0.06
- neoplasm · score 0.05
- colorectal adenocarcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86VY9-F1 | alphafold | PREDICTED | 51.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86VY9.
Amino-acid sequence (491 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM200A?
The strongest Open Targets associations for TMEM200A are coronary atherosclerosis, PHF-tau measurement, sleep duration, unipolar depression and gonorrhea.
How long is the TMEM200A protein?
The Homo sapiens TMEM200A protein (UniProt Q86VY9) is 491 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86VY9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86VY9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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