ATP-dependent chromatin remodeler CHD1L (CHD1L)
Homo sapiens — UniProt Q86WJ1
Data last refreshed: (UniProt release unknown)
Key facts
ATP-dependent chromatin remodeler CHD1L (CHD1L) is a protein from Homo sapiens identified by UniProt accession Q86WJ1, 897 residues long. MolForge cross-references it against 0 known binders and 128 disease associations.
- UniProt accession: Q86WJ1; gene symbol CHD1L.
- Organism: Homo sapiens.
- Length: 897 amino acids.
- Top disease associations (Open Targets): body height, neurodegenerative disease and Short stature.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-dependent chromatin remodeler CHD1L |
|---|---|
| UniProt accession | Q86WJ1 |
| Gene | CHD1L |
| Organism | Homo sapiens |
| Length | 897 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (128)
Diseases linked to this target (Open Targets).
- body height · score 0.43
- neurodegenerative disease · score 0.37
- Short stature · score 0.33
- appendicular lean mass · score 0.30
- diabetes mellitus · score 0.24
- body weight · score 0.22
- type 2 diabetes mellitus · score 0.18
- breast adenocarcinoma · score 0.18
- congenital anomaly of kidney and urinary tract · score 0.16
- congenital hydronephrosis · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86WJ1-F1 | alphafold | PREDICTED | 73.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86WJ1.
Amino-acid sequence (897 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHD1L?
The strongest Open Targets associations for CHD1L are body height, neurodegenerative disease, Short stature, appendicular lean mass and diabetes mellitus.
How long is the CHD1L protein?
The Homo sapiens CHD1L protein (UniProt Q86WJ1) is 897 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86WJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86WJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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