Uncharacterized protein ZSWIM9 (ZSWIM9)

About Uncharacterized protein ZSWIM9

Uncharacterized protein ZSWIM9 (ZSWIM9) is a protein from Homo sapiens identified by UniProt accession Q86XI8, 627 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Uncharacterized protein ZSWIM9
UniProt accession	Q86XI8
Gene	ZSWIM9
Organism	Homo sapiens
Length	627 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

body height · score 0.17
neurofibrillary tangles measurement · score 0.05
platelet count · score 0.02
avascular necrosis · score 0.01
squamous cell lung carcinoma · score 0.01
IGA glomerulonephritis · score 0.00
Neurodevelopmental delay · score 0.00
ulcerative colitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86XI8-F1	alphafold	PREDICTED	68.80	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86XI8.

Amino-acid sequence (627 residues)

MERPEPPPGT AAGQEEQELR ERAFFSWAEF SRFFDAWCQQ RLALFFVKSS MHLARCRWAS APPLYTLIDV LKYSYVRLVC KDVRAPSRPA VGPPQPGCPA FIIVKLSPLR DRLVVTECQL THSHPACPLE FAYYFRPGHL LANACLPVRT TNKISKQFVA PADVRRLLSY CKGRDHGVLD ALHVLEGLFR TDPEAKVKLV FVEDQAVVET VFFLTSRTRA LLRRFPRMLL VDRLPGLQGA LDLLAVLCVD GSGRARQAAC CVARPGTPSL LRFALASLLQ SAPDVKGRVR CLTAGPEVAA QLPAVRQLLP CARVQICRAQ GLETLFSKAQ ELGGAGREDP GLWSRLCRLA GASSPAAYDE ALAELHAHGP AAFVDYFERN WEPRRDMWVR FRAFEAARDL DACALVRGHR RRLLRRLSPS RGVAQCLRDL VAMQWADAAG EAVPEGPDGG GPWLEDEPGR GAQGENERVR GLETGDWGGA PKEGSIWRGA QMEKEWARAL ETRDWGGAQF EGEKGRALQI RDWRGGRLEN QKPRGLEGGV LRGSKLEKGH LRGPEIRDWR GPQLEGEKDW GLEGYVWRGS QLEDQALRGL EGYTWRVAQL EDRRSTTDLR GTQFDYERGK GESTEDR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards