Proline and serine-rich protein 1 (PROSER1)
Homo sapiens — UniProt Q86XN7
Data last refreshed: (UniProt release unknown)
Key facts
Proline and serine-rich protein 1 (PROSER1) is a protein from Homo sapiens identified by UniProt accession Q86XN7, 944 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q86XN7; gene symbol PROSER1.
- Organism: Homo sapiens.
- Length: 944 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and colorectal cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proline and serine-rich protein 1 |
|---|---|
| UniProt accession | Q86XN7 |
| Gene | PROSER1 |
| Organism | Homo sapiens |
| Length | 944 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- body height · score 0.15
- colorectal cancer · score 0.02
- Sepsis · score 0.01
- chronic kidney disease · score 0.01
- Global developmental delay · score 0.01
- neoplasm · score 0.00
- Alzheimer disease · score 0.00
- Neurodevelopmental disorder · score 0.00
- X-linked hyper-IgM syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86XN7-F1 | alphafold | PREDICTED | 44.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86XN7.
Amino-acid sequence (944 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PROSER1?
The strongest Open Targets associations for PROSER1 are neurodegenerative disease, body height, colorectal cancer, Sepsis and chronic kidney disease.
How long is the PROSER1 protein?
The Homo sapiens PROSER1 protein (UniProt Q86XN7) is 944 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86XN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86XN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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