Threonine synthase-like 2 (THNSL2)
Homo sapiens — UniProt Q86YJ6
Data last refreshed: (UniProt release unknown)
Key facts
Threonine synthase-like 2 (THNSL2) is a protein from Homo sapiens identified by UniProt accession Q86YJ6, 484 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q86YJ6; gene symbol THNSL2.
- Organism: Homo sapiens.
- Length: 484 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, hair color and basal cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Threonine synthase-like 2 |
|---|---|
| UniProt accession | Q86YJ6 |
| Gene | THNSL2 |
| Organism | Homo sapiens |
| Length | 484 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.29
- hair color · score 0.23
- basal cell carcinoma · score 0.21
- non-melanoma skin carcinoma · score 0.20
- C-reactive protein measurement · score 0.17
- drug use measurement · score 0.12
- skin carcinoma · score 0.08
- keratinocyte carcinoma · score 0.08
- Familial exudative vitreoretinopathy · score 0.04
- hair colour measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86YJ6-F1 | alphafold | PREDICTED | 95.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86YJ6.
Amino-acid sequence (484 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with THNSL2?
The strongest Open Targets associations for THNSL2 are alkaline phosphatase measurement, hair color, basal cell carcinoma, non-melanoma skin carcinoma and C-reactive protein measurement.
How long is the THNSL2 protein?
The Homo sapiens THNSL2 protein (UniProt Q86YJ6) is 484 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86YJ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86YJ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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