About Copine-8
Copine-8 (CPNE8) is a protein
from Homo sapiens identified by UniProt accession
Q86YQ8, 564 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (50)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.42
- physical activity measurement · score 0.35
- venous thromboembolism · score 0.31
- Snoring · score 0.28
- smoking status measurement · score 0.27
- insulin like growth factor measurement · score 0.22
- hip bone size · score 0.17
- hip bone mineral density · score 0.13
- health study participation · score 0.11
- daytime rest measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q86YQ8.
Amino-acid sequence (564 residues)
MDSRYNSTAG IGDLNQLSAA IPATRVEVSV SCRNLLDRDT FSKSDPICVL YVQGVGNKEW REFGRTEVID NTLNPDFVRK FILDYFFEER ENLRFDLYDV DSKSPNLSKH DFLGQVFCTL GEIVGSQGSR LEKPIVGIPG KKCGTIILTA EELNCCRDAV LMQFCANKLD KKDFFGKSDP FLVFYRSNED GSFTICHKTE VVKNTLNPVW QAFKISVRAL CNGDYDRTIK VEVYDWDRDG SHDFIGEFTT SYRELSRGQS QFNVYEVVNP KKKGKKKKYT NSGTVTLLSF LVETEVSFLD YIKGGTQINF TVAIDFTASN GNPAQPTSLH YMNPYQLNAY GMALKAVGEI VQDYDSDKMF PALGFGAKLP PDGRISHEFA LNGNPQNPYC DGIEGVMEAY YRSLKSVQLY GPTNFAPVIN HVARYASSVK DGSQYFVLLI VTDGVISDMA QTKESIVNAS KLPMSIIIVG VGPAEFDAMV ELDGDDVRVS SRGKYAERDI VQFVPFRDYI DRSGNHILSM ARLAKDVLAE IPEQFLSYMR ARGIKPSPAP PPYTPPTHVL QTQI
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