Protein WFDC10B (WFDC10B)
Homo sapiens — UniProt Q8IUB3
Data last refreshed: (UniProt release unknown)
Key facts
Protein WFDC10B (WFDC10B) is a protein from Homo sapiens identified by UniProt accession Q8IUB3, 73 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q8IUB3; gene symbol WFDC10B.
- Organism: Homo sapiens.
- Length: 73 amino acids.
- Top disease associations (Open Targets): platelet count, depressive symptom measurement and psoriasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein WFDC10B |
|---|---|
| UniProt accession | Q8IUB3 |
| Gene | WFDC10B |
| Organism | Homo sapiens |
| Length | 73 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- platelet count · score 0.05
- depressive symptom measurement · score 0.03
- psoriasis · score 0.02
- colon carcinoma · score 0.01
- Crohn's disease · score 0.01
- breast cancer · score 0.00
- Pallister-Hall syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUB3-F1 | alphafold | PREDICTED | 86.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUB3.
Amino-acid sequence (73 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WFDC10B?
The strongest Open Targets associations for WFDC10B are platelet count, depressive symptom measurement, psoriasis, colon carcinoma and Crohn's disease.
How long is the WFDC10B protein?
The Homo sapiens WFDC10B protein (UniProt Q8IUB3) is 73 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUB3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUB3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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