Keratin-associated protein 13-1 (KRTAP13-1)
Homo sapiens — UniProt Q8IUC0
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 13-1 (KRTAP13-1) is a protein from Homo sapiens identified by UniProt accession Q8IUC0, 172 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q8IUC0; gene symbol KRTAP13-1.
- Organism: Homo sapiens.
- Length: 172 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, head and neck squamous cell carcinoma and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 13-1 |
|---|---|
| UniProt accession | Q8IUC0 |
| Gene | KRTAP13-1 |
| Organism | Homo sapiens |
| Length | 172 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- head and neck squamous cell carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.11
- gastric carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUC0-F1 | alphafold | PREDICTED | 46.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUC0.
Amino-acid sequence (172 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP13-1?
The strongest Open Targets associations for KRTAP13-1 are neurodegenerative disease, head and neck squamous cell carcinoma, clear cell renal carcinoma, ovarian cancer and low grade glioma.
How long is the KRTAP13-1 protein?
The Homo sapiens KRTAP13-1 protein (UniProt Q8IUC0) is 172 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUC0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUC0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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