Keratin-associated protein 11-1 (KRTAP11-1)
Homo sapiens — UniProt Q8IUC1
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 11-1 (KRTAP11-1) is a protein from Homo sapiens identified by UniProt accession Q8IUC1, 163 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8IUC1; gene symbol KRTAP11-1.
- Organism: Homo sapiens.
- Length: 163 amino acids.
- Top disease associations (Open Targets): head and neck squamous cell carcinoma, glioblastoma multiforme and prostate adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 11-1 |
|---|---|
| UniProt accession | Q8IUC1 |
| Gene | KRTAP11-1 |
| Organism | Homo sapiens |
| Length | 163 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.18
- glioblastoma multiforme · score 0.18
- prostate adenocarcinoma · score 0.18
- neurodegenerative disease · score 0.18
- esophageal cancer · score 0.14
- sebaceous of Jadassohn nevus · score 0.04
- gastric carcinoma · score 0.01
- Salmonella Infections · score 0.00
- diabetes mellitus · score 0.00
- psoriasis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUC1-F1 | alphafold | PREDICTED | 39.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUC1.
Amino-acid sequence (163 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP11-1?
The strongest Open Targets associations for KRTAP11-1 are head and neck squamous cell carcinoma, glioblastoma multiforme, prostate adenocarcinoma, neurodegenerative disease and esophageal cancer.
How long is the KRTAP11-1 protein?
The Homo sapiens KRTAP11-1 protein (UniProt Q8IUC1) is 163 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUC1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUC1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.