Homeobox protein TGIF2LX (TGIF2LX)
Homo sapiens — UniProt Q8IUE1
Data last refreshed: (UniProt release unknown)
Key facts
Homeobox protein TGIF2LX (TGIF2LX) is a protein from Homo sapiens identified by UniProt accession Q8IUE1, 241 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8IUE1; gene symbol TGIF2LX.
- Organism: Homo sapiens.
- Length: 241 amino acids.
- Top disease associations (Open Targets): colon adenocarcinoma, colonic neoplasm and colorectal adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Homeobox protein TGIF2LX |
|---|---|
| UniProt accession | Q8IUE1 |
| Gene | TGIF2LX |
| Organism | Homo sapiens |
| Length | 241 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- colon adenocarcinoma · score 0.02
- colonic neoplasm · score 0.01
- colorectal adenocarcinoma · score 0.01
- Azoospermia · score 0.01
- Infertility · score 0.01
- non-small cell lung carcinoma · score 0.01
- neoplasm · score 0.01
- cancer · score 0.00
- benign prostatic hyperplasia · score 0.00
- male infertility · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUE1-F1 | alphafold | PREDICTED | 67.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUE1.
Amino-acid sequence (241 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TGIF2LX?
The strongest Open Targets associations for TGIF2LX are colon adenocarcinoma, colonic neoplasm, colorectal adenocarcinoma, Azoospermia and Infertility.
How long is the TGIF2LX protein?
The Homo sapiens TGIF2LX protein (UniProt Q8IUE1) is 241 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUE1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUE1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.