Ribosomal oxygenase 2 (RIOX2)
Homo sapiens — UniProt Q8IUF8
Data last refreshed: (UniProt release unknown)
Key facts
Ribosomal oxygenase 2 (RIOX2) is a protein from Homo sapiens identified by UniProt accession Q8IUF8, 465 residues long. MolForge cross-references it against 0 known binders and 145 disease associations.
- UniProt accession: Q8IUF8; gene symbol RIOX2.
- Organism: Homo sapiens.
- Length: 465 amino acids.
- Top disease associations (Open Targets): traffic air pollution measurement, neoplasm and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribosomal oxygenase 2 |
|---|---|
| UniProt accession | Q8IUF8 |
| Gene | RIOX2 |
| Organism | Homo sapiens |
| Length | 465 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (145)
Diseases linked to this target (Open Targets).
- traffic air pollution measurement · score 0.22
- neoplasm · score 0.10
- protein measurement · score 0.10
- cancer · score 0.10
- hepatocellular carcinoma · score 0.08
- glioblastoma · score 0.08
- Miyoshi myopathy · score 0.08
- COVID-19 · score 0.06
- triple-negative breast cancer · score 0.06
- isolated agammaglobulinemia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUF8-F1 | alphafold | PREDICTED | 90.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUF8.
Amino-acid sequence (465 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RIOX2?
The strongest Open Targets associations for RIOX2 are traffic air pollution measurement, neoplasm, protein measurement, cancer and hepatocellular carcinoma.
How long is the RIOX2 protein?
The Homo sapiens RIOX2 protein (UniProt Q8IUF8) is 465 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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