RNA-binding protein 45 (RBM45)
Homo sapiens — UniProt Q8IUH3
Data last refreshed: (UniProt release unknown)
Key facts
RNA-binding protein 45 (RBM45) is a protein from Homo sapiens identified by UniProt accession Q8IUH3, 476 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q8IUH3; gene symbol RBM45.
- Organism: Homo sapiens.
- Length: 476 amino acids.
- Top disease associations (Open Targets): mean platelet volume, refractive error and axial length measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RNA-binding protein 45 |
|---|---|
| UniProt accession | Q8IUH3 |
| Gene | RBM45 |
| Organism | Homo sapiens |
| Length | 476 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.27
- refractive error · score 0.10
- axial length measurement · score 0.10
- Pick disease · score 0.08
- triglyceride measurement · score 0.07
- vital capacity · score 0.06
- smoking behavior · score 0.05
- Myopia · score 0.05
- refractive error measurement · score 0.05
- Syndactyly type 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUH3-F1 | alphafold | PREDICTED | 74.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUH3.
Amino-acid sequence (476 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBM45?
The strongest Open Targets associations for RBM45 are mean platelet volume, refractive error, axial length measurement, Pick disease and triglyceride measurement.
How long is the RBM45 protein?
The Homo sapiens RBM45 protein (UniProt Q8IUH3) is 476 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUH3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUH3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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