Palmitoyltransferase ZDHHC13 (ZDHHC13)
Homo sapiens — UniProt Q8IUH4
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC13 (ZDHHC13) is a protein from Homo sapiens identified by UniProt accession Q8IUH4, 622 residues long. MolForge cross-references it against 0 known binders and 128 disease associations.
- UniProt accession: Q8IUH4; gene symbol ZDHHC13.
- Organism: Homo sapiens.
- Length: 622 amino acids.
- Top disease associations (Open Targets): leukocyte count, neurodegenerative disease and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC13 |
|---|---|
| UniProt accession | Q8IUH4 |
| Gene | ZDHHC13 |
| Organism | Homo sapiens |
| Length | 622 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (128)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.27
- neurodegenerative disease · score 0.21
- neurofibrillary tangles measurement · score 0.17
- Alopecia-intellectual disability syndrome · score 0.09
- ringed hair disease · score 0.08
- hypotrichosis simplex · score 0.08
- Alopecia universalis · score 0.08
- uncombable hair syndrome · score 0.08
- alopecia, androgenetic, 1 · score 0.07
- pili gemini · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUH4-F1 | alphafold | PREDICTED | 87.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUH4.
Amino-acid sequence (622 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC13?
The strongest Open Targets associations for ZDHHC13 are leukocyte count, neurodegenerative disease, neurofibrillary tangles measurement, Alopecia-intellectual disability syndrome and ringed hair disease.
How long is the ZDHHC13 protein?
The Homo sapiens ZDHHC13 protein (UniProt Q8IUH4) is 622 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUH4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUH4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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