Palmitoyltransferase ZDHHC17 (ZDHHC17)
Homo sapiens — UniProt Q8IUH5
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC17 (ZDHHC17) is a protein from Homo sapiens identified by UniProt accession Q8IUH5, 632 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q8IUH5; gene symbol ZDHHC17.
- Organism: Homo sapiens.
- Length: 632 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, glioblastoma multiforme and metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC17 |
|---|---|
| UniProt accession | Q8IUH5 |
| Gene | ZDHHC17 |
| Organism | Homo sapiens |
| Length | 632 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- glioblastoma multiforme · score 0.07
- metabolite measurement · score 0.07
- neoplasm · score 0.05
- basophil count · score 0.04
- Huntington disease · score 0.04
- glioblastoma · score 0.02
- polycystic ovary syndrome · score 0.01
- type 1 diabetes mellitus · score 0.01
- coronavirus infectious disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUH5-F1 | alphafold | PREDICTED | 87.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUH5.
Amino-acid sequence (632 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC17?
The strongest Open Targets associations for ZDHHC17 are neurodegenerative disease, glioblastoma multiforme, metabolite measurement, neoplasm and basophil count.
How long is the ZDHHC17 protein?
The Homo sapiens ZDHHC17 protein (UniProt Q8IUH5) is 632 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUH5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUH5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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