Plexin domain-containing protein 1 (PLXDC1)
Homo sapiens — UniProt Q8IUK5
Data last refreshed: (UniProt release unknown)
Key facts
Plexin domain-containing protein 1 (PLXDC1) is a protein from Homo sapiens identified by UniProt accession Q8IUK5, 500 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q8IUK5; gene symbol PLXDC1.
- Organism: Homo sapiens.
- Length: 500 amino acids.
- Top disease associations (Open Targets): neoplasm, hepatocellular carcinoma and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Plexin domain-containing protein 1 |
|---|---|
| UniProt accession | Q8IUK5 |
| Gene | PLXDC1 |
| Organism | Homo sapiens |
| Length | 500 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.10
- hepatocellular carcinoma · score 0.08
- cancer · score 0.07
- gut microbiome measurement · score 0.07
- glioblastoma multiforme · score 0.06
- platelet count · score 0.03
- infect · score 0.03
- infection · score 0.03
- albuminuria · score 0.03
- clear cell renal carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUK5-F1 | alphafold | PREDICTED | 72.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUK5.
Amino-acid sequence (500 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLXDC1?
The strongest Open Targets associations for PLXDC1 are neoplasm, hepatocellular carcinoma, cancer, gut microbiome measurement and glioblastoma multiforme.
How long is the PLXDC1 protein?
The Homo sapiens PLXDC1 protein (UniProt Q8IUK5) is 500 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUK5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUK5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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