Cartilage intermediate layer protein 2 (CILP2)
Homo sapiens — UniProt Q8IUL8
Data last refreshed: (UniProt release unknown)
Key facts
Cartilage intermediate layer protein 2 (CILP2) is a protein from Homo sapiens identified by UniProt accession Q8IUL8, 1156 residues long. MolForge cross-references it against 0 known binders and 135 disease associations.
- UniProt accession: Q8IUL8; gene symbol CILP2.
- Organism: Homo sapiens.
- Length: 1156 amino acids.
- Top disease associations (Open Targets): body height, platelet count and basophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cartilage intermediate layer protein 2 |
|---|---|
| UniProt accession | Q8IUL8 |
| Gene | CILP2 |
| Organism | Homo sapiens |
| Length | 1156 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (135)
Diseases linked to this target (Open Targets).
- body height · score 0.25
- platelet count · score 0.24
- basophil count · score 0.17
- mathematical ability · score 0.13
- monocyte count · score 0.13
- self reported educational attainment · score 0.11
- platelet crit · score 0.10
- eosinophil count · score 0.10
- bipolar disorder · score 0.08
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUL8-F1 | alphafold | PREDICTED | 80.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUL8.
Amino-acid sequence (1156 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CILP2?
The strongest Open Targets associations for CILP2 are body height, platelet count, basophil count, mathematical ability and monocyte count.
How long is the CILP2 protein?
The Homo sapiens CILP2 protein (UniProt Q8IUL8) is 1156 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUL8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUL8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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