Clavesin-1 (CLVS1)
Homo sapiens — UniProt Q8IUQ0
Data last refreshed: (UniProt release unknown)
Key facts
Clavesin-1 (CLVS1) is a protein from Homo sapiens identified by UniProt accession Q8IUQ0, 354 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q8IUQ0; gene symbol CLVS1.
- Organism: Homo sapiens.
- Length: 354 amino acids.
- Top disease associations (Open Targets): body mass index, body fat percentage and optic disc size measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Clavesin-1 |
|---|---|
| UniProt accession | Q8IUQ0 |
| Gene | CLVS1 |
| Organism | Homo sapiens |
| Length | 354 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- body mass index · score 0.48
- body fat percentage · score 0.40
- optic disc size measurement · score 0.36
- protein measurement · score 0.31
- bone density · score 0.31
- urate measurement · score 0.31
- body height · score 0.30
- hip circumference · score 0.27
- dermatitis · score 0.22
- lymphocyte count · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUQ0-F1 | alphafold | PREDICTED | 81.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUQ0.
Amino-acid sequence (354 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLVS1?
The strongest Open Targets associations for CLVS1 are body mass index, body fat percentage, optic disc size measurement, protein measurement and bone density.
How long is the CLVS1 protein?
The Homo sapiens CLVS1 protein (UniProt Q8IUQ0) is 354 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUQ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUQ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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