Trafficking protein particle complex subunit 5 (TRAPPC5)
Homo sapiens — UniProt Q8IUR0
Data last refreshed: (UniProt release unknown)
Key facts
Trafficking protein particle complex subunit 5 (TRAPPC5) is a protein from Homo sapiens identified by UniProt accession Q8IUR0, 188 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q8IUR0; gene symbol TRAPPC5.
- Organism: Homo sapiens.
- Length: 188 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, multiple sclerosis and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Trafficking protein particle complex subunit 5 |
|---|---|
| UniProt accession | Q8IUR0 |
| Gene | TRAPPC5 |
| Organism | Homo sapiens |
| Length | 188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- multiple sclerosis · score 0.43
- Parkinson disease · score 0.43
- Alzheimer disease · score 0.43
- lysosomal storage disease · score 0.43
- neuroinflammatory disorder · score 0.25
- breast adenocarcinoma · score 0.10
- hepatocellular carcinoma · score 0.07
- blood protein measurement · score 0.03
- resistin measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUR0-F1 | alphafold | PREDICTED | 86.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUR0.
Amino-acid sequence (188 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRAPPC5?
The strongest Open Targets associations for TRAPPC5 are neurodegenerative disease, multiple sclerosis, Parkinson disease, Alzheimer disease and lysosomal storage disease.
How long is the TRAPPC5 protein?
The Homo sapiens TRAPPC5 protein (UniProt Q8IUR0) is 188 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUR0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUR0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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