RELT-like protein 1 (RELL1)
Homo sapiens — UniProt Q8IUW5
Data last refreshed: (UniProt release unknown)
Key facts
RELT-like protein 1 (RELL1) is a protein from Homo sapiens identified by UniProt accession Q8IUW5, 271 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q8IUW5; gene symbol RELL1.
- Organism: Homo sapiens.
- Length: 271 amino acids.
- Top disease associations (Open Targets): benign adult familial myoclonic epilepsy, attention deficit hyperactivity disorder and X-linked dominant intellectual disability - epilepsy syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RELT-like protein 1 |
|---|---|
| UniProt accession | Q8IUW5 |
| Gene | RELL1 |
| Organism | Homo sapiens |
| Length | 271 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- benign adult familial myoclonic epilepsy · score 0.04
- attention deficit hyperactivity disorder · score 0.04
- X-linked dominant intellectual disability - epilepsy syndrome · score 0.04
- serum alanine aminotransferase measurement · score 0.03
- serum gamma-glutamyl transferase measurement · score 0.02
- Leishmaniasis · score 0.01
- ovarian carcinoma · score 0.01
- cytomegalovirus infection · score 0.01
- Alzheimer disease · score 0.01
- juvenile dermatomyositis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IUW5-F1 | alphafold | PREDICTED | 60.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IUW5.
Amino-acid sequence (271 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RELL1?
The strongest Open Targets associations for RELL1 are benign adult familial myoclonic epilepsy, attention deficit hyperactivity disorder, X-linked dominant intellectual disability - epilepsy syndrome, serum alanine aminotransferase measurement and serum gamma-glutamyl transferase measurement.
How long is the RELL1 protein?
The Homo sapiens RELL1 protein (UniProt Q8IUW5) is 271 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IUW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IUW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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