Palmitoyltransferase ZDHHC21 (ZDHHC21)
Homo sapiens — UniProt Q8IVQ6
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC21 (ZDHHC21) is a protein from Homo sapiens identified by UniProt accession Q8IVQ6, 265 residues long. MolForge cross-references it against 0 known binders and 207 disease associations.
- UniProt accession: Q8IVQ6; gene symbol ZDHHC21.
- Organism: Homo sapiens.
- Length: 265 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, self reported educational attainment and age at first birth measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC21 |
|---|---|
| UniProt accession | Q8IVQ6 |
| Gene | ZDHHC21 |
| Organism | Homo sapiens |
| Length | 265 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (207)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- self reported educational attainment · score 0.26
- age at first birth measurement · score 0.26
- protein measurement · score 0.22
- mathematical ability · score 0.11
- insomnia measurement · score 0.10
- schizophrenia · score 0.10
- substance abuse · score 0.09
- attention deficit hyperactivity disorder · score 0.09
- antisocial behaviour measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IVQ6-F1 | alphafold | PREDICTED | 87.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IVQ6.
Amino-acid sequence (265 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC21?
The strongest Open Targets associations for ZDHHC21 are neurodegenerative disease, self reported educational attainment, age at first birth measurement, protein measurement and mathematical ability.
How long is the ZDHHC21 protein?
The Homo sapiens ZDHHC21 protein (UniProt Q8IVQ6) is 265 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IVQ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IVQ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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