Type III endosome membrane protein TEMP (C1orf210)
Homo sapiens — UniProt Q8IVY1
Data last refreshed: (UniProt release unknown)
Key facts
Type III endosome membrane protein TEMP (C1orf210) is a protein from Homo sapiens identified by UniProt accession Q8IVY1, 113 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q8IVY1; gene symbol C1orf210.
- Organism: Homo sapiens.
- Length: 113 amino acids.
- Top disease associations (Open Targets): kidney injury molecule 1 measurement, blood phosphate measurement and cystatin C measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Type III endosome membrane protein TEMP |
|---|---|
| UniProt accession | Q8IVY1 |
| Gene | C1orf210 |
| Organism | Homo sapiens |
| Length | 113 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- kidney injury molecule 1 measurement · score 0.08
- blood phosphate measurement · score 0.03
- cystatin C measurement · score 0.03
- creatinine measurement · score 0.03
- hemoglobin measurement · score 0.03
- colorectal cancer · score 0.01
- Systemic lupus erythematosus · score 0.01
- Crohn's disease · score 0.01
- hepatocellular carcinoma · score 0.01
- clear cell renal carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IVY1-F1 | alphafold | PREDICTED | 64.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IVY1.
Amino-acid sequence (113 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1orf210?
The strongest Open Targets associations for C1orf210 are kidney injury molecule 1 measurement, blood phosphate measurement, cystatin C measurement, creatinine measurement and hemoglobin measurement.
How long is the C1orf210 protein?
The Homo sapiens C1orf210 protein (UniProt Q8IVY1) is 113 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IVY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IVY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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