DCN1-like protein 3 (DCUN1D3)
Homo sapiens — UniProt Q8IWE4
Data last refreshed: (UniProt release unknown)
Key facts
DCN1-like protein 3 (DCUN1D3) is a protein from Homo sapiens identified by UniProt accession Q8IWE4, 304 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q8IWE4; gene symbol DCUN1D3.
- Organism: Homo sapiens.
- Length: 304 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, urate measurement and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DCN1-like protein 3 |
|---|---|
| UniProt accession | Q8IWE4 |
| Gene | DCUN1D3 |
| Organism | Homo sapiens |
| Length | 304 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.10
- urate measurement · score 0.09
- diastolic blood pressure · score 0.08
- eosinophil count · score 0.08
- eosinophil percentage of leukocytes · score 0.07
- body height · score 0.06
- erythrocyte count · score 0.05
- MODY · score 0.05
- diabetes mellitus, permanent neonatal 4 · score 0.04
- permanent neonatal diabetes mellitus 1 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IWE4-F1 | alphafold | PREDICTED | 79.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IWE4.
Amino-acid sequence (304 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DCUN1D3?
The strongest Open Targets associations for DCUN1D3 are mean corpuscular volume, urate measurement, diastolic blood pressure, eosinophil count and eosinophil percentage of leukocytes.
How long is the DCUN1D3 protein?
The Homo sapiens DCUN1D3 protein (UniProt Q8IWE4) is 304 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IWE4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IWE4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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