Saitohin (STH)
Homo sapiens — UniProt Q8IWL8
Data last refreshed: (UniProt release unknown)
Key facts
Saitohin (STH) is a protein from Homo sapiens identified by UniProt accession Q8IWL8, 128 residues long. MolForge cross-references it against 0 known binders and 138 disease associations.
- UniProt accession: Q8IWL8; gene symbol STH.
- Organism: Homo sapiens.
- Length: 128 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, osteoarthritis, hip and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Saitohin |
|---|---|
| UniProt accession | Q8IWL8 |
| Gene | STH |
| Organism | Homo sapiens |
| Length | 128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (138)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.15
- osteoarthritis, hip · score 0.15
- reticulocyte count · score 0.15
- mean reticulocyte volume · score 0.15
- type 1 diabetes mellitus · score 0.15
- mean corpuscular volume · score 0.14
- vital capacity · score 0.14
- Red cell distribution width · score 0.14
- erythrocyte count · score 0.14
- risk-taking behaviour · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IWL8-F1 | alphafold | PREDICTED | 56.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IWL8.
Amino-acid sequence (128 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STH?
The strongest Open Targets associations for STH are alkaline phosphatase measurement, osteoarthritis, hip, reticulocyte count, mean reticulocyte volume and type 1 diabetes mellitus.
How long is the STH protein?
The Homo sapiens STH protein (UniProt Q8IWL8) is 128 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IWL8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IWL8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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