Serine/threonine-protein kinase LMTK2 (LMTK2)
Homo sapiens — UniProt Q8IWU2
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase LMTK2 (LMTK2) is a protein from Homo sapiens identified by UniProt accession Q8IWU2, 1503 residues long. MolForge cross-references it against 0 known binders and 153 disease associations.
- UniProt accession: Q8IWU2; gene symbol LMTK2.
- Organism: Homo sapiens.
- Length: 1503 amino acids.
- Top disease associations (Open Targets): prostate carcinoma, serum gamma-glutamyl transferase measurement and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase LMTK2 |
|---|---|
| UniProt accession | Q8IWU2 |
| Gene | LMTK2 |
| Organism | Homo sapiens |
| Length | 1503 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (153)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.38
- serum gamma-glutamyl transferase measurement · score 0.34
- smoking status measurement · score 0.29
- urate measurement · score 0.27
- uric acid measurement · score 0.20
- type 2 diabetes mellitus · score 0.20
- cancer · score 0.20
- neuroticism measurement · score 0.17
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IWU2-F1 | alphafold | PREDICTED | 46.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IWU2.
Amino-acid sequence (1503 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LMTK2?
The strongest Open Targets associations for LMTK2 are prostate carcinoma, serum gamma-glutamyl transferase measurement, smoking status measurement, urate measurement and uric acid measurement.
How long is the LMTK2 protein?
The Homo sapiens LMTK2 protein (UniProt Q8IWU2) is 1503 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IWU2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IWU2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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