Contactin-4 (CNTN4)
Homo sapiens — UniProt Q8IWV2
Data last refreshed: (UniProt release unknown)
Key facts
Contactin-4 (CNTN4) is a protein from Homo sapiens identified by UniProt accession Q8IWV2, 1026 residues long. MolForge cross-references it against 0 known binders and 121 disease associations.
- UniProt accession: Q8IWV2; gene symbol CNTN4.
- Organism: Homo sapiens.
- Length: 1026 amino acids.
- Top disease associations (Open Targets): schizophrenia, blood protein measurement and bipolar disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Contactin-4 |
|---|---|
| UniProt accession | Q8IWV2 |
| Gene | CNTN4 |
| Organism | Homo sapiens |
| Length | 1026 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (121)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.46
- blood protein measurement · score 0.42
- bipolar disorder · score 0.41
- mathematical ability · score 0.41
- chronotype measurement · score 0.39
- bone density · score 0.37
- urate measurement · score 0.37
- autism spectrum disorder · score 0.36
- anorexia nervosa · score 0.35
- lip and oral cavity carcinoma · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IWV2-F1 | alphafold | PREDICTED | 86.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IWV2.
Amino-acid sequence (1026 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNTN4?
The strongest Open Targets associations for CNTN4 are schizophrenia, blood protein measurement, bipolar disorder, mathematical ability and chronotype measurement.
How long is the CNTN4 protein?
The Homo sapiens CNTN4 protein (UniProt Q8IWV2) is 1026 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IWV2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IWV2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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