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C-Maf-inducing protein (CMIP)

Homo sapiens — UniProt Q8IY22

Gene: CMIPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

C-Maf-inducing protein (CMIP) is a protein from Homo sapiens identified by UniProt accession Q8IY22, 773 residues long. MolForge cross-references it against 0 known binders and 158 disease associations.

  • UniProt accession: Q8IY22; gene symbol CMIP.
  • Organism: Homo sapiens.
  • Length: 773 amino acids.
  • Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, triglyceride measurement and BMI-adjusted waist-hip ratio.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameC-Maf-inducing protein
UniProt accessionQ8IY22
GeneCMIP
OrganismHomo sapiens
Length773 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (158)

Diseases linked to this target (Open Targets).

  • high density lipoprotein cholesterol measurement · score 0.54
  • triglyceride measurement · score 0.53
  • BMI-adjusted waist-hip ratio · score 0.53
  • type 2 diabetes mellitus · score 0.52
  • testosterone measurement · score 0.52
  • heel bone mineral density · score 0.51
  • alcohol consumption measurement · score 0.50
  • sex hormone-binding globulin measurement · score 0.50
  • neutrophil count · score 0.50
  • body height · score 0.49

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8IY22-F1alphafoldPREDICTED78.77—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IY22.

Amino-acid sequence (773 residues)

MDVTSSSGGG GDPRQIEETK PLLGGDVSAP EGTKMGAVPC RRALLLCNGM RYKLLQEGDI QVCVIRHPRT FLSKILTSKF LRRWEPHHLT LADNSLASAT PTGYMENSVS YSAIEDVQLL SWENAPKYCL QLTIPGGTVL LQAANSYLRD QWFHSLQWKK KIYKYKKVLS NPSRWEVVLK EIRTLVDMAL TSPLQDDSIN QAPLEIVSKL LSENTNLTTQ EHENIIVAIA PLLENNHPPP DLCEFFCKHC RERPRSMVVI EVFTPVVQRI LKHNMDFGKC PRLRLFTQEY ILALNELNAG MEVVKKFIQS MHGPTGHCPH PRVLPNLVAV CLAAIYSCYE EFINSRDNSP SLKEIRNGCQ QPCDRKPTLP LRLLHPSPDL VSQEATLSEA RLKSVVVASS EIHVEVERTS TAKPALTASA GNDSEPNLID CLMVSPACST MSIELGPQAD RTLGCYVEIL KLLSDYDDWR PSLASLLQPI PFPKEALAHE KFTKELKYVI QRFAEDPRQE VHSCLLSVRA GKDGWFQLYS PGGVACDDDG ELFASMVHIL MGSCYKTKKF LLSLAENKLG PCMLLALRGN QTMVEILCLM LEYNIIDNND TQLQIISTLE STDVGKRMYE QLCDRQRELK ELQRKGGPTR LTLPSKSTDA DLARLLSSGS FGNLENLSLA FTNVTSACAE HLIKLPSLKQ LNLWSTQFGD AGLRLLSEHL TMLQVLNLCE TPVTDAGLLA LSSMKSLCSL NMNSTKLSAD TYEDLKAKLP NLKEVDVRYT EAW

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CMIP?

The strongest Open Targets associations for CMIP are high density lipoprotein cholesterol measurement, triglyceride measurement, BMI-adjusted waist-hip ratio, type 2 diabetes mellitus and testosterone measurement.

How long is the CMIP protein?

The Homo sapiens CMIP protein (UniProt Q8IY22) is 773 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8IY22
GeneCMIP
OrganismHomo sapiens
Length773
Binders0
Diseases158
View on UniProt