MICAL-like protein 2 (MICALL2)
Homo sapiens — UniProt Q8IY33
Data last refreshed: (UniProt release unknown)
Key facts
MICAL-like protein 2 (MICALL2) is a protein from Homo sapiens identified by UniProt accession Q8IY33, 904 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q8IY33; gene symbol MICALL2.
- Organism: Homo sapiens.
- Length: 904 amino acids.
- Top disease associations (Open Targets): Joubert syndrome 1, cognitive inhibition measurement and BMI-adjusted waist circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MICAL-like protein 2 |
|---|---|
| UniProt accession | Q8IY33 |
| Gene | MICALL2 |
| Organism | Homo sapiens |
| Length | 904 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- Joubert syndrome 1 · score 0.33
- cognitive inhibition measurement · score 0.27
- BMI-adjusted waist circumference · score 0.22
- restless legs syndrome · score 0.21
- sitting height measurement · score 0.20
- blood protein measurement · score 0.19
- serum gamma-glutamyl transferase measurement · score 0.13
- monocyte count · score 0.12
- genetic disorder · score 0.12
- rosacea · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IY33-F1 | alphafold | PREDICTED | 55.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IY33.
Amino-acid sequence (904 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MICALL2?
The strongest Open Targets associations for MICALL2 are Joubert syndrome 1, cognitive inhibition measurement, BMI-adjusted waist circumference, restless legs syndrome and sitting height measurement.
How long is the MICALL2 protein?
The Homo sapiens MICALL2 protein (UniProt Q8IY33) is 904 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IY33 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IY33 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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