Solute carrier family 35 member F3 (SLC35F3)
Homo sapiens — UniProt Q8IY50
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 35 member F3 (SLC35F3) is a protein from Homo sapiens identified by UniProt accession Q8IY50, 421 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q8IY50; gene symbol SLC35F3.
- Organism: Homo sapiens.
- Length: 421 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, chronic obstructive pulmonary disease and hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 35 member F3 |
|---|---|
| UniProt accession | Q8IY50 |
| Gene | SLC35F3 |
| Organism | Homo sapiens |
| Length | 421 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- chronic obstructive pulmonary disease · score 0.30
- hypertension · score 0.30
- triglyceride measurement · score 0.27
- sleep duration · score 0.27
- diverticular disease · score 0.26
- diverticulitis · score 0.19
- metabolic syndrome · score 0.06
- metabolite measurement · score 0.05
- response to anticonvulsant · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IY50-F1 | alphafold | PREDICTED | 75.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IY50.
Amino-acid sequence (421 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC35F3?
The strongest Open Targets associations for SLC35F3 are neurodegenerative disease, chronic obstructive pulmonary disease, hypertension, triglyceride measurement and sleep duration.
How long is the SLC35F3 protein?
The Homo sapiens SLC35F3 protein (UniProt Q8IY50) is 421 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IY50 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IY50 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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