Serine/threonine-protein kinase NIM1 (NIM1K)
Homo sapiens — UniProt Q8IY84
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase NIM1 (NIM1K) is a protein from Homo sapiens identified by UniProt accession Q8IY84, 436 residues long. MolForge cross-references it against 5 known binders and 43 disease associations.
- UniProt accession: Q8IY84; gene symbol NIM1K.
- Organism: Homo sapiens.
- Length: 436 amino acids.
- Top disease associations (Open Targets): body fat percentage, body height and aspartate aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase NIM1 |
|---|---|
| UniProt accession | Q8IY84 |
| Gene | NIM1K |
| Organism | Homo sapiens |
| Length | 436 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.42
- body height · score 0.36
- aspartate aminotransferase measurement · score 0.29
- low density lipoprotein triglyceride measurement · score 0.29
- high density lipoprotein cholesterol measurement · score 0.29
- serum alanine aminotransferase measurement · score 0.29
- sex hormone-binding globulin measurement · score 0.29
- body mass index · score 0.27
- fat body mass · score 0.25
- lymphocyte count · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IY84-F1 | alphafold | PREDICTED | 82.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IY84.
Amino-acid sequence (436 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NIM1K?
The strongest Open Targets associations for NIM1K are body fat percentage, body height, aspartate aminotransferase measurement, low density lipoprotein triglyceride measurement and high density lipoprotein cholesterol measurement.
How long is the NIM1K protein?
The Homo sapiens NIM1K protein (UniProt Q8IY84) is 436 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IY84 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IY84 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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