Transmembrane protein 192 (TMEM192)
Homo sapiens — UniProt Q8IY95
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 192 (TMEM192) is a protein from Homo sapiens identified by UniProt accession Q8IY95, 271 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8IY95; gene symbol TMEM192.
- Organism: Homo sapiens.
- Length: 271 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, neuroticism measurement and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 192 |
|---|---|
| UniProt accession | Q8IY95 |
| Gene | TMEM192 |
| Organism | Homo sapiens |
| Length | 271 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.32
- neuroticism measurement · score 0.26
- mathematical ability · score 0.22
- hepatocellular carcinoma · score 0.01
- cardiovascular disease · score 0.01
- neoplasm · score 0.01
- cancer · score 0.00
- Burkitts lymphoma · score 0.00
- oral squamous cell carcinoma · score 0.00
- ovarian neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IY95-F1 | alphafold | PREDICTED | 76.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IY95.
Amino-acid sequence (271 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM192?
The strongest Open Targets associations for TMEM192 are self reported educational attainment, neuroticism measurement, mathematical ability, hepatocellular carcinoma and cardiovascular disease.
How long is the TMEM192 protein?
The Homo sapiens TMEM192 protein (UniProt Q8IY95) is 271 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IY95 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IY95 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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