Serine/arginine repetitive matrix protein 1 (SRRM1)
Homo sapiens — UniProt Q8IYB3
Data last refreshed: (UniProt release unknown)
Key facts
Serine/arginine repetitive matrix protein 1 (SRRM1) is a protein from Homo sapiens identified by UniProt accession Q8IYB3, 904 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q8IYB3; gene symbol SRRM1.
- Organism: Homo sapiens.
- Length: 904 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, chronic lymphocytic leukemia and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/arginine repetitive matrix protein 1 |
|---|---|
| UniProt accession | Q8IYB3 |
| Gene | SRRM1 |
| Organism | Homo sapiens |
| Length | 904 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- chronic lymphocytic leukemia · score 0.15
- heel bone mineral density · score 0.10
- platelet crit · score 0.04
- hemoglobin measurement · score 0.04
- hematocrit · score 0.04
- platelet component distribution width · score 0.04
- red blood cell density measurement · score 0.03
- mean corpuscular hemoglobin concentration · score 0.03
- diastolic blood pressure · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYB3-F1 | alphafold | PREDICTED | 51.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYB3.
Amino-acid sequence (904 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SRRM1?
The strongest Open Targets associations for SRRM1 are neurodegenerative disease, chronic lymphocytic leukemia, heel bone mineral density, platelet crit and hemoglobin measurement.
How long is the SRRM1 protein?
The Homo sapiens SRRM1 protein (UniProt Q8IYB3) is 904 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYB3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYB3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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