Elongin-A2 (ELOA2)
Homo sapiens — UniProt Q8IYF1
Data last refreshed: (UniProt release unknown)
Key facts
Elongin-A2 (ELOA2) is a protein from Homo sapiens identified by UniProt accession Q8IYF1, 753 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q8IYF1; gene symbol ELOA2.
- Organism: Homo sapiens.
- Length: 753 amino acids.
- Top disease associations (Open Targets): HIV infection, creatinine measurement and conscientiousness measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Elongin-A2 |
|---|---|
| UniProt accession | Q8IYF1 |
| Gene | ELOA2 |
| Organism | Homo sapiens |
| Length | 753 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.58
- creatinine measurement · score 0.12
- conscientiousness measurement · score 0.12
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- self reported educational attainment · score 0.06
- intelligence · score 0.04
- schizophrenia · score 0.04
- P-selectin glycoprotein ligand 1 measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYF1-F1 | alphafold | PREDICTED | 54.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYF1.
Amino-acid sequence (753 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELOA2?
The strongest Open Targets associations for ELOA2 are HIV infection, creatinine measurement, conscientiousness measurement, Familial prostate cancer and prostate carcinoma.
How long is the ELOA2 protein?
The Homo sapiens ELOA2 protein (UniProt Q8IYF1) is 753 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYF1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYF1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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