Testis-expressed protein 11 (TEX11)
Homo sapiens — UniProt Q8IYF3
Data last refreshed: (UniProt release unknown)
Key facts
Testis-expressed protein 11 (TEX11) is a protein from Homo sapiens identified by UniProt accession Q8IYF3, 940 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q8IYF3; gene symbol TEX11.
- Organism: Homo sapiens.
- Length: 940 amino acids.
- Top disease associations (Open Targets): spermatogenic failure, X-linked, 2, azoospermia and male infertility with azoospermia or oligozoospermia due to single gene mutation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Testis-expressed protein 11 |
|---|---|
| UniProt accession | Q8IYF3 |
| Gene | TEX11 |
| Organism | Homo sapiens |
| Length | 940 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- spermatogenic failure, X-linked, 2 · score 0.62
- azoospermia · score 0.54
- male infertility with azoospermia or oligozoospermia due to single gene mutation · score 0.38
- uterine fibroid · score 0.36
- Uterine leiomyoma · score 0.30
- neurodegenerative disease · score 0.29
- genetic disorder · score 0.19
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- partial chromosome Y deletion · score 0.06
- spermatogenic failure 59 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYF3-F1 | alphafold | PREDICTED | 86.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYF3.
Amino-acid sequence (940 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TEX11?
The strongest Open Targets associations for TEX11 are spermatogenic failure, X-linked, 2, azoospermia, male infertility with azoospermia or oligozoospermia due to single gene mutation, uterine fibroid and Uterine leiomyoma.
How long is the TEX11 protein?
The Homo sapiens TEX11 protein (UniProt Q8IYF3) is 940 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYF3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYF3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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