Leucine-rich repeat-containing protein 56 (LRRC56)
Homo sapiens — UniProt Q8IYG6
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 56 (LRRC56) is a protein from Homo sapiens identified by UniProt accession Q8IYG6, 542 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q8IYG6; gene symbol LRRC56.
- Organism: Homo sapiens.
- Length: 542 amino acids.
- Top disease associations (Open Targets): ciliary dyskinesia, primary, 39, primary ciliary dyskinesia and HbA1c measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 56 |
|---|---|
| UniProt accession | Q8IYG6 |
| Gene | LRRC56 |
| Organism | Homo sapiens |
| Length | 542 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- ciliary dyskinesia, primary, 39 · score 0.67
- primary ciliary dyskinesia · score 0.37
- HbA1c measurement · score 0.04
- congenitally corrected transposition of the great arteries · score 0.03
- high density lipoprotein cholesterol measurement · score 0.03
- systemic lupus erythematosus · score 0.02
- reticulocyte count · score 0.02
- systemic scleroderma · score 0.02
- myxedema · score 0.02
- reticulocyte measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYG6-F1 | alphafold | PREDICTED | 55.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYG6.
Amino-acid sequence (542 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC56?
The strongest Open Targets associations for LRRC56 are ciliary dyskinesia, primary, 39, primary ciliary dyskinesia, HbA1c measurement, congenitally corrected transposition of the great arteries and high density lipoprotein cholesterol measurement.
How long is the LRRC56 protein?
The Homo sapiens LRRC56 protein (UniProt Q8IYG6) is 542 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYG6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYG6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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