ZZ-type zinc finger-containing protein 3 (ZZZ3)
Homo sapiens — UniProt Q8IYH5
Data last refreshed: (UniProt release unknown)
Key facts
ZZ-type zinc finger-containing protein 3 (ZZZ3) is a protein from Homo sapiens identified by UniProt accession Q8IYH5, 903 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.
- UniProt accession: Q8IYH5; gene symbol ZZZ3.
- Organism: Homo sapiens.
- Length: 903 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, mean corpuscular volume and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ZZ-type zinc finger-containing protein 3 |
|---|---|
| UniProt accession | Q8IYH5 |
| Gene | ZZZ3 |
| Organism | Homo sapiens |
| Length | 903 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (130)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- mean corpuscular volume · score 0.22
- body mass index · score 0.22
- platelet count · score 0.20
- creatinine measurement · score 0.19
- body height · score 0.19
- glomerular filtration rate · score 0.17
- neurodegenerative disease · score 0.15
- self reported educational attainment · score 0.13
- physical activity measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYH5-F1 | alphafold | PREDICTED | 53.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYH5.
Amino-acid sequence (903 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZZZ3?
The strongest Open Targets associations for ZZZ3 are breast adenocarcinoma, mean corpuscular volume, body mass index, platelet count and creatinine measurement.
How long is the ZZZ3 protein?
The Homo sapiens ZZZ3 protein (UniProt Q8IYH5) is 903 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYH5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYH5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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