PILR alpha-associated neural protein (PIANP)
Homo sapiens — UniProt Q8IYJ0
Data last refreshed: (UniProt release unknown)
Key facts
PILR alpha-associated neural protein (PIANP) is a protein from Homo sapiens identified by UniProt accession Q8IYJ0, 282 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q8IYJ0; gene symbol PIANP.
- Organism: Homo sapiens.
- Length: 282 amino acids.
- Top disease associations (Open Targets): genetic disorder, sex hormone-binding globulin measurement and Autism.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PILR alpha-associated neural protein |
|---|---|
| UniProt accession | Q8IYJ0 |
| Gene | PIANP |
| Organism | Homo sapiens |
| Length | 282 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.12
- sex hormone-binding globulin measurement · score 0.03
- Autism · score 0.02
- colorectal cancer · score 0.02
- neoplasm · score 0.02
- atypical teratoid rhabdoid tumor · score 0.01
- anxiety · score 0.01
- pituitary cancer · score 0.01
- bacterial urinary tract infection · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYJ0-F1 | alphafold | PREDICTED | 54.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYJ0.
Amino-acid sequence (282 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PIANP?
The strongest Open Targets associations for PIANP are genetic disorder, sex hormone-binding globulin measurement, Autism, colorectal cancer and neoplasm.
How long is the PIANP protein?
The Homo sapiens PIANP protein (UniProt Q8IYJ0) is 282 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYJ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYJ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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