Copine-9 (CPNE9)
Homo sapiens — UniProt Q8IYJ1
Data last refreshed: (UniProt release unknown)
Key facts
Copine-9 (CPNE9) is a protein from Homo sapiens identified by UniProt accession Q8IYJ1, 553 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q8IYJ1; gene symbol CPNE9.
- Organism: Homo sapiens.
- Length: 553 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, central nervous system cancer and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Copine-9 |
|---|---|
| UniProt accession | Q8IYJ1 |
| Gene | CPNE9 |
| Organism | Homo sapiens |
| Length | 553 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- central nervous system cancer · score 0.04
- glioblastoma multiforme · score 0.03
- astrocytoma · score 0.02
- psoriasis · score 0.02
- ependymoma · score 0.02
- autism · score 0.01
- primitive neuroectodermal tumor · score 0.01
- multiple myeloma · score 0.01
- Miyoshi myopathy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYJ1-F1 | alphafold | PREDICTED | 89.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYJ1.
Amino-acid sequence (553 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CPNE9?
The strongest Open Targets associations for CPNE9 are neurodegenerative disease, central nervous system cancer, glioblastoma multiforme, astrocytoma and psoriasis.
How long is the CPNE9 protein?
The Homo sapiens CPNE9 protein (UniProt Q8IYJ1) is 553 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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