Uncharacterized protein C10orf67, mitochondrial (C10orf67)
Homo sapiens — UniProt Q8IYJ2
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C10orf67, mitochondrial (C10orf67) is a protein from Homo sapiens identified by UniProt accession Q8IYJ2, 551 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q8IYJ2; gene symbol C10orf67.
- Organism: Homo sapiens.
- Length: 551 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, type 2 diabetes mellitus and pancreatic agenesis 2.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C10orf67, mitochondrial |
|---|---|
| UniProt accession | Q8IYJ2 |
| Gene | C10orf67 |
| Organism | Homo sapiens |
| Length | 551 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.41
- type 2 diabetes mellitus · score 0.41
- pancreatic agenesis 2 · score 0.34
- brain volume measurement · score 0.17
- high density lipoprotein cholesterol measurement · score 0.04
- colorectal adenocarcinoma · score 0.04
- body height · score 0.03
- protein measurement · score 0.03
- non-small cell lung carcinoma · score 0.03
- cystatin C measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYJ2-F1 | alphafold | PREDICTED | 69.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYJ2.
Amino-acid sequence (551 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C10orf67?
The strongest Open Targets associations for C10orf67 are heel bone mineral density, type 2 diabetes mellitus, pancreatic agenesis 2, brain volume measurement and high density lipoprotein cholesterol measurement.
How long is the C10orf67 protein?
The Homo sapiens C10orf67 protein (UniProt Q8IYJ2) is 551 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYJ2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYJ2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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