Tektin-like protein 1 (TEKTL1)
Homo sapiens — UniProt Q8IYK2
Data last refreshed: (UniProt release unknown)
Key facts
Tektin-like protein 1 (TEKTL1) is a protein from Homo sapiens identified by UniProt accession Q8IYK2, 499 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q8IYK2; gene symbol TEKTL1.
- Organism: Homo sapiens.
- Length: 499 amino acids.
- Top disease associations (Open Targets): pancreatic adenocarcinoma, Infertility and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tektin-like protein 1 |
|---|---|
| UniProt accession | Q8IYK2 |
| Gene | TEKTL1 |
| Organism | Homo sapiens |
| Length | 499 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- pancreatic adenocarcinoma · score 0.03
- Infertility · score 0.00
- neoplasm · score 0.00
- Reduced sperm motility · score 0.00
- carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYK2-F1 | alphafold | PREDICTED | 78.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYK2.
Amino-acid sequence (499 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TEKTL1?
The strongest Open Targets associations for TEKTL1 are pancreatic adenocarcinoma, Infertility, neoplasm, Reduced sperm motility and carcinoma.
How long is the TEKTL1 protein?
The Homo sapiens TEKTL1 protein (UniProt Q8IYK2) is 499 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYK2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYK2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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