Procollagen galactosyltransferase 2 (COLGALT2)
Homo sapiens — UniProt Q8IYK4
Data last refreshed: (UniProt release unknown)
Key facts
Procollagen galactosyltransferase 2 (COLGALT2) is a protein from Homo sapiens identified by UniProt accession Q8IYK4, 626 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q8IYK4; gene symbol COLGALT2.
- Organism: Homo sapiens.
- Length: 626 amino acids.
- Top disease associations (Open Targets): body height, osteoarthritis and osteoarthritis, hip.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Procollagen galactosyltransferase 2 |
|---|---|
| UniProt accession | Q8IYK4 |
| Gene | COLGALT2 |
| Organism | Homo sapiens |
| Length | 626 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- body height · score 0.47
- osteoarthritis · score 0.40
- osteoarthritis, hip · score 0.40
- body weight · score 0.38
- sitting height measurement · score 0.35
- lean body mass · score 0.34
- fat body mass · score 0.33
- appendicular lean mass · score 0.30
- medical procedure · score 0.28
- reticulocyte count · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYK4-F1 | alphafold | PREDICTED | 88.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYK4.
Amino-acid sequence (626 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COLGALT2?
The strongest Open Targets associations for COLGALT2 are body height, osteoarthritis, osteoarthritis, hip, body weight and sitting height measurement.
How long is the COLGALT2 protein?
The Homo sapiens COLGALT2 protein (UniProt Q8IYK4) is 626 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYK4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYK4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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