GTP-binding protein REM 2 (REM2)
Homo sapiens — UniProt Q8IYK8
Data last refreshed: (UniProt release unknown)
Key facts
GTP-binding protein REM 2 (REM2) is a protein from Homo sapiens identified by UniProt accession Q8IYK8, 340 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q8IYK8; gene symbol REM2.
- Organism: Homo sapiens.
- Length: 340 amino acids.
- Top disease associations (Open Targets): migraine disorder, neutrophil count and eosinophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GTP-binding protein REM 2 |
|---|---|
| UniProt accession | Q8IYK8 |
| Gene | REM2 |
| Organism | Homo sapiens |
| Length | 340 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- migraine disorder · score 0.09
- neutrophil count · score 0.08
- eosinophil percentage of leukocytes · score 0.05
- body height · score 0.03
- macula measurement · score 0.02
- cortical surface area measurement · score 0.02
- mathematical ability · score 0.02
- eosinophil count · score 0.02
- systolic blood pressure · score 0.02
- Fasciitis · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYK8-F1 | alphafold | PREDICTED | 67.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYK8.
Amino-acid sequence (340 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with REM2?
The strongest Open Targets associations for REM2 are migraine disorder, neutrophil count, eosinophil percentage of leukocytes, body height and macula measurement.
How long is the REM2 protein?
The Homo sapiens REM2 protein (UniProt Q8IYK8) is 340 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYK8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYK8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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