Threonine synthase-like 1 (THNSL1)
Homo sapiens — UniProt Q8IYQ7
Data last refreshed: (UniProt release unknown)
Key facts
Threonine synthase-like 1 (THNSL1) is a protein from Homo sapiens identified by UniProt accession Q8IYQ7, 743 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q8IYQ7; gene symbol THNSL1.
- Organism: Homo sapiens.
- Length: 743 amino acids.
- Top disease associations (Open Targets): reticulocyte count, neurodegenerative disease and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Threonine synthase-like 1 |
|---|---|
| UniProt accession | Q8IYQ7 |
| Gene | THNSL1 |
| Organism | Homo sapiens |
| Length | 743 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.40
- neurodegenerative disease · score 0.39
- body height · score 0.29
- reticulocyte measurement · score 0.26
- brain volume measurement · score 0.24
- neuroinflammatory disorder · score 0.14
- lymphocyte count · score 0.08
- eosinophil count · score 0.08
- leukocyte count · score 0.08
- platelet count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYQ7-F1 | alphafold | PREDICTED | 87.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYQ7.
Amino-acid sequence (743 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with THNSL1?
The strongest Open Targets associations for THNSL1 are reticulocyte count, neurodegenerative disease, body height, reticulocyte measurement and brain volume measurement.
How long is the THNSL1 protein?
The Homo sapiens THNSL1 protein (UniProt Q8IYQ7) is 743 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYQ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYQ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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