Biorientation of chromosomes in cell division protein 1-like 2 (BOD1L2)
Homo sapiens — UniProt Q8IYS8
Data last refreshed: (UniProt release unknown)
Key facts
Biorientation of chromosomes in cell division protein 1-like 2 (BOD1L2) is a protein from Homo sapiens identified by UniProt accession Q8IYS8, 172 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q8IYS8; gene symbol BOD1L2.
- Organism: Homo sapiens.
- Length: 172 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, type 2 diabetes mellitus and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Biorientation of chromosomes in cell division protein 1-like 2 |
|---|---|
| UniProt accession | Q8IYS8 |
| Gene | BOD1L2 |
| Organism | Homo sapiens |
| Length | 172 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.23
- type 2 diabetes mellitus · score 0.13
- neurofibrillary tangles measurement · score 0.11
- DNA methylation · score 0.10
- systolic blood pressure · score 0.05
- chronic myeloproliferative disorder · score 0.04
- linear and whorled nevoid hypermelanosis · score 0.04
- idiopathic hypereosinophilic syndrome · score 0.04
- urate measurement · score 0.04
- bone density · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYS8-F1 | alphafold | PREDICTED | 73.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYS8.
Amino-acid sequence (172 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BOD1L2?
The strongest Open Targets associations for BOD1L2 are gut microbiome measurement, type 2 diabetes mellitus, neurofibrillary tangles measurement, DNA methylation and systolic blood pressure.
How long is the BOD1L2 protein?
The Homo sapiens BOD1L2 protein (UniProt Q8IYS8) is 172 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYS8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYS8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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