Golgi-associated RAB2 interactor protein 4 (GARIN4)
Homo sapiens — UniProt Q8IYT1
Data last refreshed: (UniProt release unknown)
Key facts
Golgi-associated RAB2 interactor protein 4 (GARIN4) is a protein from Homo sapiens identified by UniProt accession Q8IYT1, 594 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q8IYT1; gene symbol GARIN4.
- Organism: Homo sapiens.
- Length: 594 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, erythrocyte count and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi-associated RAB2 interactor protein 4 |
|---|---|
| UniProt accession | Q8IYT1 |
| Gene | GARIN4 |
| Organism | Homo sapiens |
| Length | 594 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.12
- erythrocyte count · score 0.12
- leukocyte count · score 0.12
- platelet count · score 0.12
- mean corpuscular volume · score 0.12
- mean corpuscular hemoglobin concentration · score 0.12
- mean platelet volume · score 0.12
- neutrophil count · score 0.12
- eosinophil count · score 0.12
- basophil count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYT1-F1 | alphafold | PREDICTED | 51.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYT1.
Amino-acid sequence (594 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GARIN4?
The strongest Open Targets associations for GARIN4 are Red cell distribution width, erythrocyte count, leukocyte count, platelet count and mean corpuscular volume.
How long is the GARIN4 protein?
The Homo sapiens GARIN4 protein (UniProt Q8IYT1) is 594 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYT1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYT1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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