Coiled-coil domain-containing protein 170 (CCDC170)
Homo sapiens — UniProt Q8IYT3
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 170 (CCDC170) is a protein from Homo sapiens identified by UniProt accession Q8IYT3, 715 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q8IYT3; gene symbol CCDC170.
- Organism: Homo sapiens.
- Length: 715 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 170 |
|---|---|
| UniProt accession | Q8IYT3 |
| Gene | CCDC170 |
| Organism | Homo sapiens |
| Length | 715 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.53
- bone quantitative ultrasound measurement · score 0.52
- bone density · score 0.52
- lymphocyte count · score 0.48
- endometriosis · score 0.45
- breast carcinoma · score 0.45
- alkaline phosphatase measurement · score 0.44
- eosinophil count · score 0.41
- spine bone mineral density · score 0.41
- hypertension · score 0.41
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYT3-F1 | alphafold | PREDICTED | 81.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYT3.
Amino-acid sequence (715 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC170?
The strongest Open Targets associations for CCDC170 are heel bone mineral density, bone quantitative ultrasound measurement, bone density, lymphocyte count and endometriosis.
How long is the CCDC170 protein?
The Homo sapiens CCDC170 protein (UniProt Q8IYT3) is 715 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYT3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYT3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.