Ubiquilin-like protein (UBQLNL)
Homo sapiens — UniProt Q8IYU4
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquilin-like protein (UBQLNL) is a protein from Homo sapiens identified by UniProt accession Q8IYU4, 475 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q8IYU4; gene symbol UBQLNL.
- Organism: Homo sapiens.
- Length: 475 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, mean platelet volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquilin-like protein |
|---|---|
| UniProt accession | Q8IYU4 |
| Gene | UBQLNL |
| Organism | Homo sapiens |
| Length | 475 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.05
- mean platelet volume · score 0.05
- platelet count · score 0.05
- Hypercholesterolemia · score 0.04
- low density lipoprotein cholesterol measurement · score 0.04
- bilirubin measurement · score 0.04
- coronary artery disease · score 0.04
- serum alanine aminotransferase measurement · score 0.04
- alkaline phosphatase measurement · score 0.04
- apolipoprotein B measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYU4-F1 | alphafold | PREDICTED | 54.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYU4.
Amino-acid sequence (475 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBQLNL?
The strongest Open Targets associations for UBQLNL are sex hormone-binding globulin measurement, mean platelet volume, platelet count, Hypercholesterolemia and low density lipoprotein cholesterol measurement.
How long is the UBQLNL protein?
The Homo sapiens UBQLNL protein (UniProt Q8IYU4) is 475 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYU4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYU4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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