Stabilizer of axonemal microtubules 1 (SAXO1)
Homo sapiens — UniProt Q8IYX7
Data last refreshed: (UniProt release unknown)
Key facts
Stabilizer of axonemal microtubules 1 (SAXO1) is a protein from Homo sapiens identified by UniProt accession Q8IYX7, 474 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q8IYX7; gene symbol SAXO1.
- Organism: Homo sapiens.
- Length: 474 amino acids.
- Top disease associations (Open Targets): platelet count, body height and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Stabilizer of axonemal microtubules 1 |
|---|---|
| UniProt accession | Q8IYX7 |
| Gene | SAXO1 |
| Organism | Homo sapiens |
| Length | 474 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- platelet count · score 0.35
- body height · score 0.33
- type 2 diabetes mellitus · score 0.19
- heel bone mineral density · score 0.17
- prostate carcinoma · score 0.15
- mean platelet volume · score 0.14
- testosterone measurement · score 0.12
- sex hormone-binding globulin measurement · score 0.08
- appendicitis · score 0.08
- pulse pressure measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IYX7-F1 | alphafold | PREDICTED | 67.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IYX7.
Amino-acid sequence (474 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SAXO1?
The strongest Open Targets associations for SAXO1 are platelet count, body height, type 2 diabetes mellitus, heel bone mineral density and prostate carcinoma.
How long is the SAXO1 protein?
The Homo sapiens SAXO1 protein (UniProt Q8IYX7) is 474 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IYX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IYX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.