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Protein FAM200C (FAM200C)

Homo sapiens — UniProt Q8IZ13

Gene: FAM200CHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein FAM200C (FAM200C) is a protein from Homo sapiens identified by UniProt accession Q8IZ13, 594 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

  • UniProt accession: Q8IZ13; gene symbol FAM200C.
  • Organism: Homo sapiens.
  • Length: 594 amino acids.
  • Top disease associations (Open Targets): asthma, allergic rhinitis and Eczematoid dermatitis.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein FAM200C
UniProt accessionQ8IZ13
GeneFAM200C
OrganismHomo sapiens
Length594 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (19)

Diseases linked to this target (Open Targets).

  • asthma · score 0.23
  • allergic rhinitis · score 0.21
  • Eczematoid dermatitis · score 0.21
  • eosinophil count · score 0.20
  • eosinophil percentage of leukocytes · score 0.16
  • Inhalant adrenergic use measurement · score 0.15
  • seasonal allergic rhinitis · score 0.15
  • allergic disease · score 0.15
  • neurofibrillary tangles measurement · score 0.11
  • systemic lupus erythematosus · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8IZ13-F1alphafoldPREDICTED82.08—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IZ13.

Amino-acid sequence (594 residues)

MSKKRKWDDD YVRYWFTCTT EVDGTQRPQC VLCNSVFSNA DLRPSKLSDH FNRQHGGVAG HDLNSLKHMP APSDQSETLK AFGVASHEDT LLQASYQFAY LCAKEKNPHT VAEKLVKPCA LEIAQIVLGP DAQKKLQQVP LSDDVIHSRI DEMSQDILQQ VLEDIKASPL KVGIQLAETT DMDDCSQLMA FVRYIKEREI VEEFLFCEPL QLSMKGIDVF NLFRDFFLKH KIALDVCGSV CTDGASSMLG ENSEFVAYVK KEIPHIVVTH CLLNPHALVI KTLPTKLRDA LFTVVRVINF IKGRAPNHRL FQAFFEEIGI EYSVLLFHTE MRWLSRGQIL THIFEMYEEI NQFLHHKSSN LVDGFENKEF KIHLAYLADL FKHLNELSAS MQRTGMNTVS AREKLSAFVR KFPFWQKRIE KRNFTNFPFL EEIIVSDNEG IFIAAEITLH LQQLSNFFHG YFSIGDLNEA SKWILDPFLF NIDFVDDSYL MKNDLAELRA SGQILMEFET MKLEDFWCAQ FTAFPNLAKT ALEILMPFAT TYLCELGFSS LLHFKTKSRS CFNLSDDIRV AISKKVPRFS DIIEQKLQLQ QKSL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAM200C?

The strongest Open Targets associations for FAM200C are asthma, allergic rhinitis, Eczematoid dermatitis, eosinophil count and eosinophil percentage of leukocytes.

How long is the FAM200C protein?

The Homo sapiens FAM200C protein (UniProt Q8IZ13) is 594 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8IZ13
GeneFAM200C
OrganismHomo sapiens
Length594
Binders0
Diseases19
View on UniProt