About Solute carrier family 22 member 15
Solute carrier family 22 member 15 (SLC22A15) is a protein
from Homo sapiens identified by UniProt accession
Q8IZD6, 547 residues long.
MolForge cross-references it against 0 known binders and
111 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (111)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- Familial short QT syndrome · score 0.08
- Brugada syndrome · score 0.08
- Romano-Ward syndrome · score 0.08
- familial atrial fibrillation · score 0.08
- hypertrophic cardiomyopathy · score 0.08
- Arrhythmogenic right ventricular dysplasia · score 0.08
- pancreatic neoplasm · score 0.07
- Familial progressive cardiac conduction defect · score 0.07
- ventricular fibrillation, paroxysmal familial, type 1 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q8IZD6.
Amino-acid sequence (547 residues)
MEVEEAFQAV GEMGIYQMYL CFLLAVLLQL YVATEAILIA LVGATPSYHW DLAELLPNQS HGNQSAGEDQ AFGDWLLTAN GSEIHKHVHF SSSFTSIASE WFLIANRSYK VSAASSFFFS GVFVGVISFG QLSDRFGRKK VYLTGFALDI LFAIANGFSP SYEFFAVTRF LVGMMNGGMS LVAFVLLNEC VGTAYWALAG SIGGLFFAVG IAQYALLGYF IRSWRTLAIL VNLQGTVVFL LSLFIPESPR WLYSQGRLSE AEEALYLIAK RNRKLKCTFS LTHPANRSCR ETGSFLDLFR YRVLLGHTLI LMFIWFVCSL VYYGLTLSAG DLGGSIYANL ALSGLIEIPS YPLCIYLINQ KWFGRKRTLS AFLCLGGLAC LIVMFLPEKK DTGVFAVVNS HSLSLLGKLT ISAAFNIVYI YTSELYPTVI RNVGLGTCSM FSRVGGIIAP FIPSLKYVQW SLPFIVFGAT GLTSGLLSLL LPETLNSPLL ETFSDLQVYS YRRLGEEALS LQALDPQQCV DKESSLGSES EEEEEFYDAD EETQMIK
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